With rising interest in GLP-1 medications like Ozempic, Wegovy, and Mounjaro, many people have turned to compounded semaglutide for weight loss as a more affordable, accessible alternative. Searches for “compounded semaglutide 2025,” “GLP-1 weight loss,” and “Ozempic alternative without insurance” are trending as users seek clarity on what’s safe—and what’s no longer available.

In this guide, we’ll address one of the biggest questions of the year: Is compounded semaglutide still available in 2025? We’ll also explore safe weight loss alternatives, the FDA’s latest stance, and where to turn next.

💊 What Is Compounded Semaglutide?

Compounded semaglutide is a custom-made version of the active ingredient in Ozempic or Wegovy, typically prepared by a licensed compounding pharmacy when the FDA-approved version is on the drug shortage list.

These compounded versions became popular for:

Lower cost (typically $250–$400/month)
Easier access (especially via telehealth)
Weight loss support without insurance

But as of April 2025, the game has changed.

🚨 FDA Update: Compounded Semaglutide Is No Longer Authorized

The FDA has removed semaglutide from its official shortage list. This change means compounding pharmacies can no longer legally prepare or distribute semaglutide-based medications, unless the drug is explicitly listed as being in shortage.

This is a critical update. Many people still searching “is compounded semaglutide still available?” may not realize that unless the brand-name drug (Ozempic, Wegovy) becomes unavailable again, compounded versions are now considered non-compliant by FDA standards.

⚠️ Important: Some online sellers and clinics may continue to offer compounded semaglutide labeled as “research peptides” or “semaglutide sodium.” These are not FDA-approved and may pose serious health risks.

🧠 Misinformation About Availability

Many influencers and forums are still recommending compounded versions without noting the change in FDA policy. This confusion makes it more important than ever to educate consumers on:

The legality of compounded semaglutide in 2025
How to access safe, regulated GLP-1 medications
What affordable alternatives are still on the market

✅ What Are Your Options Now?

With compounded semaglutide off the table for now, here are the trusted alternatives for GLP-1 weight loss in 2025:

1. Telehealth GLP-1 Programs (FDA-Approved)

Companies like Nurx, Ro, and PlushCare offer legitimate access to Ozempic, Wegovy, or Zepbound via online consultation. While not “cheap,” these platforms often work with manufacturer savings cards, payment plans, or assistance programs.

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2. Tirzepatide (Zepbound or Mounjaro)

If semaglutide is out of reach, tirzepatide may be worth exploring. Some patients report faster weight loss with this newer GLP-1/GIP combo. Compounded tirzepatide is also affected by FDA rules, but brand-name versions may now be more accessible with insurance or discount programs.

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3. Non-GLP-1 Medications

Other weight loss medications like Contrave, Qsymia, or metformin may offer modest benefits. These alternatives tend to cost less and may still help with appetite control and blood sugar regulation.

4. Holistic Weight Loss Support

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